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"ENDOTRACK- Tracking the Endocytic Routes of Polypeptide Growth Factor Receptor Complexes and their Modulatory Role on Signaling" is an Integrated Project funded by the European Commission as part of its Sixth Framework Programme (EC Contract). The project started on February 1, 2006 and is scheduled to run over a period of four years. The aim of this project is to gain conceptual advance into the signaling function of growth factors from an unconventional perspective, namely by exploring the role of endocytic trafficking in the modulation of growth factor signaling.